Hepatocyte growth factor predicts failure of Fontan circulation
نویسندگان
چکیده
منابع مشابه
Gene transfer of hepatocyte growth factor attenuates postinfarction heart failure.
BACKGROUND Despite advances in surgical and percutaneous coronary revascularization, ongoing ischemia that is not amenable to standard revascularization techniques is a major cause of morbidity and mortality. Hepatocyte Growth Factor (HGF) has potent angiogenic and anti-apoptotic activities, and this study evaluated the functional and biochemical effects of HGF gene transfer in a rat model of p...
متن کاملHepatocyte growth factor signalizes peritoneal membrane failure in peritoneal dialysis
BACKGROUND Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (FWT) and small-solute transport. METHODS We performed 4-hour, 3.86% PET wit...
متن کاملThe Fontan Circulation
The original Fontan procedure was first introduced in the 1970s. The concept behind this surgical technique was revolutionary. It has subsequently transformed the lives of children born with complex congenital heart disease which was once thought to be inoperable and resulted in early death. The procedure itself has had several modifications over the decades, with subsequent improvements in lon...
متن کاملHepatocyte Growth Factor
Hepatocyte growth factor (HGF) exerts biological activity through the Met receptor tyrosine kinase. HGF plays essential roles in the embryonic development of the liver and placenta, and in the migration of myogenic precursor cells. In mature tissues, HGF plays roles in tissue protection and regeneration, including in the liver and kidney. HGF participates in invasion, metastasis, and drug resis...
متن کاملThe Fontan circulation.
Correspondence to: Professor Marc Gewillig, Pediatric Cardiology, Gasthuisberg University Hospital, B 3000 Leuven, Belgium; marc.gewillig@ uzleuven.be _________________________ A normal mammal cardiovascular system consists postnatally of a double—pulmonary and systemic—circuit, connected in series, powered by a double pump—the ‘‘right’’ and ‘‘left’’ heart. Many complex cardiac malformations ar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ESC Heart Failure
سال: 2020
ISSN: 2055-5822,2055-5822
DOI: 10.1002/ehf2.12943